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Clinical trials, 2 deaths occurred in 12 reported cases of acute overdosage with anafranil either alone or in combination with other drugs.

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Clomipramine is used to treat symptoms of obsessive-compulsive disorder (OCD) such as recurrent thoughts or feelings and repetitive actions.

If you need surgery.tell the surgeon ahead of time that you are using clomipramine. You may need to stop using the medicine for a short time.

Tell the doctor right away if you notice worsening depression/other psychiatric conditions.unusual behavior changes (including possible suicidal thoughts/attempts).or other mental/mood changes (including new/worsening anxiety.panic attacks.trouble sleeping.irritability.hostile/angry feelings.impulsive actions.anafranil cost restlessness.very rapid speech). Be especially watchful for these symptoms when a new antidepressant is started or when the dose is changed.

Clomipramine shares pharmacological properties with Class IA and Class III antiarrhythmic medications. Co-administration increases the risk for QT prolongation and life-threatening arrhythmias. For this reason.use of clomipramine should be avoided with bretylium.dofetilide (Tikosyn).dronedarone (Multaq).flecainide (Tambocor).sotalol (Betapace).quinidine (Quinidex).procainamide (Pronestyl).propafenone (Rythmol).ranolazine (Ranexa).ibutilide (Corvert).and others.

Get medical help right away if you have any very serious side effects.including. black stools.chest pain.fainting.slow/fast/irregular heartbeat.seizures.vomit that looks like coffee grounds.eye pain/swelling/redness.widened changes (such as seeing rainbows around lights at anafranil cost).

Read the Medication Guide provided by your pharmacist before you start taking clomipramine and each time you get a refill. If you have any questions.ask your doctor or pharmacist.

Other medications can affect the removal of clomipramine from your body.which may affect how clomipramine works. Examples include artemether/lumefantrine.barbiturates (such as phenobarbital).cimetidine.haloperidol.certain drugs for heart rhythm (such as flecainide/propafenone).certain HIV protease inhibitors (such as fosamprenavir).phenothiazines (such as thioridazine).certain anti-seizure drugs (such as phenytoin).terbinafine.

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