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– itraconazole greatly increases the concentration of atorlip-ez atorvastatin in plasma, apparently due to inhibition of itraconazole its metabolism in the liver that occurs with the participation of isoenzyme cyp3a4; increased risk of myopathy.
Description about Atorlip.
Myopathy order atorlip cv be considered in any patient with diffuse myalgias.muscle tenderness or weakness.and/or marked elevation of CPK. Patients should be advised to report promptly unexplained muscle pain.tenderness.or weakness.particularly if accompanied by malaise or feveror if muscle signs and symptoms persist after discontinuing ATORLIP . ATORLIP therapy should be discontinued if markedly order atorlip cv CPK levels occur or myopathy is diagnosed or suspected.
Atoris had no clinically significant order atorlip cv on prothrombin time when administered to patients receiving chronic warfarin treatment.
Immunosuppressants. Immunosuppressants such as cyclosporine and tacrolimus can produce nephrotoxicity with decreases in creatinine clearance and rises in serum creatinine.and because renal excretion is the primary elimination route of fibrate drugs including fenofibrate.there is a risk that an interaction will lead to deterioration or renal function. The benefits and risks of using ATORLIP-F with immunosuppressants and other potentially nephrotoxic agents should be carefully considered.and the lowest effective dose employed and renal function monitored.
You should not take Atorlip if you are allergic to it.if you are pregnant or breast-feeding.or if you have liver disease.
Atorvastatin is a selective.competitive inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase.the rate-limiting enzyme that converts HMG-CoA to mevalonate.a precursor of sterols.including cholesterol. Cholesterol and triglycerides (TG) circulate in the bloodstream as part of lipoprotein complexes. With ultracentrifugation.these complexes separate into high-density lipoprotein (HDL).intermediate-density lipoprotein (IDL).low-density lipoprotein (Order atorlip cv) and very-low-density lipoprotein (VLDL) fractions. TG and cholesterol in the liver are incorporated into VLDL and released into the plasma for delivery to peripheral tissues. LDL is formed from VLDL and is catabolized primarily through the high-affinity LDL receptor. Clinical and pathologic studies show that elevated plasma levels of total cholesterol (total-C).LDL-cholesterol (LDL-C) and apolipoprotein B (apo B) promote human atherosclerosis and are risk factors for developing cardiovascular disease (CVD).while increased levels of HDL-cholesterol (HDL-Order atorlip cv) are associated with a decreased cardiovascular risk.
Fenofibrateshould be initiated at a lower dose in patients having mild to moderately impaired renal function and it should be avoided in patients with severe renal impairment. As ATORLIP-F contains 145 mg of fenofibrate.it should be avoided in order atorlip cv renal impairment patients.
There are several ways the heart becomes enlarged. When.due to certain causes.it is unable to meet the blood supply of the body.and tries to pump out blood beyond its normal capacity.it stresses out. It is one of the most important part of the body. The human heart is a rather vital organ within the body.
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